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E7 protein also interacts with the ATR DNA damage pathway to increase the degradation of claspin, a crucial controller of the ATR/CHK1 signaling axis, thereby reducing the DNA damage checkpoint control in the G2 phase [108]

Substances that inhibit coloration may be included

The PICO laser also stimulates the proliferation of macrophages in the targeted area, enhancing their phagocytic activity to clear the broken-down pigments

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